OBESITY & GALL BLADDER DISEASES

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Danish researchers found that the higher BMI, the higher risk factor for gallstones espically in women.

Elevated BMI has been associated with an increased risk of gallstones, but it’s unclear if the relationship is causal, since there is a possibilty that another factor simultaneously raises BMI and causes gallstones, such as high-fat diet or physical inactivity.

 

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Overall, the researchers found that increasing BMI was associated with an increased risk of gallstones That association was significant for both men and women, although it was stronger for women.

Mechanisms by which obesity may cause gallstone disease include that obesity may increase two hepatic cholesterol synthesis , which lead to the development of cholesterol gallstones.

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